At Editas Medicine, we are pioneering the possible. Our mission and commitment is to translate the power and potential of the CRISPR/Cas12a and CRISPR/Cas9 genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for a broad class of diseases.

Why Choose Editas?

At Editas Medicine, we’re a team of passionate problem solvers, harnessing the power and potential of CRISPR gene editing to transform the future of medicine. Driven by a shared purpose to serve people living with serious diseases, we succeed together through collaboration, mutual respect, and innovation. If you want to be part of a team where your voice is heard and respected, where you can operate at the forefront of gene editing, and push the boundaries of what’s possible in medicine, come join us and become an Editor!

Decoding The Role:

Editas is seeking a highly motivated Associate Scientist to join our Genomics & Bioinformatics Group. In this role, you will use various CRISPR delivery systems to execute high-throughput screens to identify lead guides across our internal programs. You will be responsible for experimental design, analysis, and summarizing screens. In addition to screening efforts, you will be responsible for inventory and distribution of reagents within Sample Management.

An ideal candidate has extensive experience handling and troubleshooting primary cells (HSC, T cells, Hepatocytes) and has experience screening in these cell types using various CRISPR delivery systems, including RNP and LNPs. The candidate should have a strong track record of creative thinking, strong drive, and the ability to be nimble while supporting multiple programs at a given time. Familiarity with liquid handling robots, such as the Biomek I7, and acoustic liquid transfers, like the Echo, is a plus.

The position requires working effectively in a multi-disciplinary team, excellent written and verbal communication skills, and a capacity for creativity and innovation to efficiently execute screens that support the company achieve corporate objectives.

Requirements

Characterizing Your Impact:

As the Associate Scientist, Genomics and Bioinformatics you will:

Contribute to experimental design, execute screens, with editing and/or functional assays as readouts for internal programs.

Analyze and summarize screening results into proper documentation (ELN, Study Reports) and presentation slides.
Assist with Sample Management Support.

The Ideal Transcript:

To thrive in this role, you’ll need:

Minimum Qualifications

B.S. in cell biology, or related field with 5+ years of relevant experience in industry; or M.S. in cell or molecular biology with 3+ years of relevant experience in industry
Independently design and run screening experiments, extract gDNA, submit for sequencing, analyze, and present data
Extensive experience handling primary cell lines. Proficient in performing cell-based assay development. Demonstrated ability to handle multiple cell lines simultaneously.
Proficient in multi-color flow cytometry, including design and data analysis using FlowJo.
Experience working with different screening modalities such as guide RNAs and LNPs.
Demonstrated ability to formulate both RNP and LNPs
Capable of independently using data analysis software such as PRISM, Tableau
Desire to learn new techniques and share expertise with colleagues
Self-motivated, detail-oriented problem solver with strong troubleshooting skills
Outstanding organizational skills and ability to multi-task in a fast-paced environment
Excellent communication and interpersonal skills fostering effective teamwork

Fundamentals That Set You Apart

Preferred Qualifications

Proficient in executing and analyzing functional assays including ELISAs and western blots
Familiar in molecular biology analyses such as qPCR and ddPCR
Prior experience operating lab automation including both liquid handling robots (Biomek I7s, Mantis, Echo) and plate readers (Envision). Bonus if prior experience writing methods on liquid handling robots.

Benefits

Editas provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Stock Purchase Plan, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy.

Salary Range:

$105,000 - $118,000

Pay Transparency

Editas Medicine is committed to transparency and accuracy in our hiring practices. The anticipated salary range for each position is posted within the role. The final salary offer will be determined based on a comprehensive assessment of the candidate's qualifications, including education, training, and relevant experience. Additional factors such as external market conditions, the role's criticality, and internal equity will also be considered. Editas Medicine's compensation philosophy ensures fair and equitable pay practices.

Aspire to be an Editor? We invite you to apply and join us at the forefront of innovation and be a key contributor to realizing Editas Medicine's mission of developing transformative medicines for people living with serious diseases.

Editas Medicine

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Associate Scientist, Genomics and Bioinformatics