Positions: Postdoctoral Fellow and Research Technician

Expertise sought: Human iPSC-Derived Microglia, Brain Organoids, Neuroinflammation, and HIV Research

Duration: At least 5 Years

Play Scale: NIH Recommended

Note: US and Europe candidates are preferred. Experience in iPSCs is crucial to have.

Contact: mxt108@gmail.com (Thomas Jefferson University, Philadelphia)

A highly motivated Postdoctoral Fellow and Research Technician are sought to join laboratory investigating the molecular and cellular mechanisms underlying HIV persistence, neuroinflammation, accelerated aging, and neurodegeneration. The laboratory utilizes cutting-edge human induced pluripotent stem cell (iPSC)-derived microglia, cerebral organoids, and advanced genomic approaches to identify novel therapeutic targets and develop innovative interventions for HIV-associated and age-related neurological disorders.

The successful candidates will participate in exciting multidisciplinary projects focused on understanding how HIV infection, chronic inflammation, and drugs of abuse alter brain function and contribute to neurocognitive impairment, neurovascular dysfunction, and accelerated aging.

Application Materials: Cover letter describing research interests and career goals; 2) Curriculum vitae (CV); 3) Names and contact information for three references; 4) Representative publications (post-Doc Fellow).

NOTE: Candidates with experience in human iPSC-derived microglia, brain organoids, neuroinflammation, HIV biology, single-cell genomics are particularly encouraged to apply.

Research experience (post-Doc Fellow) in the following areas:

Human iPSC-derived microglia and other brain cells
Generation and characterization of cerebral and brain organoids
HIV infection and persistence in the central nervous system
Neuroinflammation and inflammasome signaling
Aging and age-associated neurodegenerative mechanisms
HIV infection and latency models
CRISPR/Cas genome engineering
Single-cell RNA sequencing (scRNA-seq)
Other common Molecular and cellular biology techniques

Responsibilities (post-Doc Fellow):

Design and conduct independent research projects
Mentor students and junior laboratory personnel
Analyze and interpret experimental data
Prepare manuscripts and grant applications
Present findings at scientific meetings

Qualifications (post-Doc Fellow):

Ph.D. in Neuroscience, Cell Biology, Molecular Biology, Immunology, Virology, Stem Cell Biology, Biomedical Sciences, or a related field. The candidate should have strong publication record demonstrating research productivity.

Qualifications - Research Technician:

B.S. or M.S. degree in Biology, Neuroscience, Biochemistry, Biomedical Sciences, or a related field, Experience with mammalian cell culture preferred, Familiarity with molecular biology techniques, Strong organizational and record-keeping skills, Ability to work effectively in a multidisciplinary environment.

Responsibilities - Research Technician:

Maintain and expand iPSC cultures
Assist with generation and maintenance of cerebral organoids
Perform molecular and cellular biology experiments
Assist with data collection and laboratory organization and maintain detailed laboratory records

Pay: $54,032.23 - $65,071.07 per year

Benefits:

401(k)
Dental insurance
Employee assistance program
Parental leave
Retirement plan
Tuition reimbursement

Work Location: In person

Thomas Jefferson University

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Postdoctoral Fellow and Research Technician