RELOCATION TO BEAUTIFUL SYDNEY, AUSTRALIA IS REQUIRED FOR THIS ROLE
About BCAL Diagnostics
BCAL Diagnostics (ASX: BDX) is an Australian-based biotechnology company pioneering the development of non-invasive diagnostic assays for cancer detection. Leveraging lipidomics, molecular biology, and advanced bioinformatics, BCAL aims to deliver accessible and accurate blood-based tests that transform how cancer is detected and managed globally.
Position Overview
The Director of Genomics will lead BCAL’s genomics strategy and operations, driving the translation of molecular biomarkers into clinically and commercially viable diagnostic assays. The successful candidate will oversee the development, validation, and commercialisation of PCR- and sequencing-based diagnostic assays, including DNA- and RNA-based assays. This is a senior leadership role requiring deep technical expertise, cross-functional collaboration, and strategic oversight across R&D, clinical development, and product commercialisation.
Key Responsibilities
- Strategic Leadership: Define and execute BCAL’s genomics strategy across discovery, assay development, clinical validation, and regulatory translation.
- Assay Development: Lead design, optimisation, and validation of PCR (qPCR, digital PCR, multiplex) and sequencing assays for diagnostic use.
- Technical Oversight: Guide analytical and clinical validation studies in accordance with ISO 15189, NPAAC and TGA IVD frameworks.
- Team Leadership: Build, mentor, and manage a multidisciplinary team of molecular biologists, bioinformaticians, and laboratory scientists.
- Cross-Functional Collaboration: Partner with clinical, regulatory, and commercial teams to ensure smooth translation of R&D outputs into regulated products.
- External Partnerships: Manage collaborations with CROs, academic institutions, and industry partners for assay development and technology transfer.
- Innovation & IP: Identify emerging genomic technologies, lead feasibility assessments, and contribute to IP generation and protection.
- Governance & Compliance: Ensure adherence to quality systems, ethical standards, and corporate governance requirements for diagnostic development.
Qualifications & Experience
- PhD in Molecular Biology, Genomics, Biochemistry, or related field (or equivalent advanced degree).
- 10+ years’ experience in molecular diagnostics or biotechnology, with a strong record of assay development and commercialization (minimum of 3 years in a commercial organisation)
- Proven expertise in PCR and sequencing technologies, which include one or more of: qPCR, dPCR, amplicon sequencing, methylation sequencing, and bioinformatics integration.
- Demonstrated experience leading scientific teams in a regulated (IVD or CLIA/ISO-accredited) environment.
- Deep understanding of diagnostic assay design, analytical/clinical validation, and regulatory submission pathways (TGA, FDA, CE-IVDR).
- Strong publication and/or patent record in molecular diagnostics or genomics.
- Excellent communication, leadership, and stakeholder management skills.
Desirable Attributes
- Experience in liquid biopsy, biomarker discovery, or cancer diagnostics.
- Familiarity with multi-omic data integration or multi-omic assay development
- Commercial acumen with understanding of product lifecycle management and market access considerations.
Job Type: Full-time
Pay: $100,000.00 - $150,000.00 per year
Benefits:
- Paid time off
- Parental leave
Application Question(s):
- Are you willing to return or relocate to Australia?
Work Location: In person
