Job Title: Genomic Curator for Cancer
Department: Product
Reports to: Associate Director of Product Quality
Position Type: Part Time Non-Exempt
PRIORITY RESPONSIBILITY
Provide written interpretations following the AMP guidelines for the evaluation of the clinical significance of biomarkers in cancer for the purpose of NGS-based genetic testing. Golden Helix provides an implementation of the somatic scoring guidelines published by AMP with widely adopted analysis software VarSeq and VSClinical. In this part-time, flexible, remote-friendly position, you will join the team that maintains and builds out Golden Helix CancerKB: a knowledgebase of expert-written interpretations for the most common biomarkers in the most common cancers.
ESSENTIAL DUTIES
Genomic Biomarker Interpreter
- Generate clear, concise clinical interpretations for cancer biomarkers in the context of Next-Generation Sequencing (NGS)-based targeted molecular therapy clinical tests
- Identify and classify variants in accordance with Golden Helix’s variant curation process
- Master the relevant capabilities of Golden Helix’s software
- Other duties as directed.
QUALIFICATIONS
- PhD in Oncological Sciences, Molecular Genetics, Human Genetics or is currently employed as clinical variant scientist.
- Experience writing variant interpretations or biomarker interpretations.
- Strong working knowledge of laboratory genetics and genomics (e.g. target capture/amplification and next-generation sequencing).
- Strong understanding and well-versed in applying FDA and EMA regulations, NCCN, ESMO, and WHO Guidelines.
- Well organized, self-directed and highly detailed.
- Strong oral and written communication skills.
MEASUREMENTS
The Genomic Curator for Cancer will be measured on:
- Quality of interpretations written
- Efficiency in synthesizing diverse sources of information into clear and comprehensive interpretations.
How to Apply:
Interested applicants are asked to submit their resume and sample of writing (preferably variant or biomarker interpretations) to personnel at goldenhelix.com.
Job Type: Part-time
Application Question(s):
- Would you be able to share an example of your writing as it pertains to variant interpretation? Ideally, this would be in the context of interpreting somatic mutations in cancer and the clinical evidence around that variant as a biomarker for targeted molecular therapy.
Education:
Experience:
- Molecular biology: 1 year (Preferred)
Work Location: Remote
