Summary

NIST is seeking a Bioinformatician to develop Artificial Intelligence (AI) bioinformatic workflows to analyze complex flow cytometry and genomics data. Key responsibilities include collaborating with cross-functional teams to extract insights from large datasets, optimizing machine learning models, and communicating technical findings to diverse stakeholders.

This notice is issued under direct-hire authority to recruit talent to occupations for which NIST has a severe shortage of candidates.

Learn more about this agency

This job is open to

The public

U.S. Citizens, Nationals or those who owe allegiance to the U.S.

Career transition (CTAP, ICTAP, RPL)

Federal employees whose job, agency or department was eliminated and are eligible for priority over other applicants.

Clarification from the agency

U.S. Citizens

Duties

As a Bioinformatician supporting NIST's Biomarker and Genomic Sciences Group, your core responsibilities include:

Workflow Development: Build robust, reproducible bioinformatics pipelines for flow cytometry and genomics.
AI Implementation: Design and deploy machine learning models to analyze complex multiparameter datasets and optimize them for scalability and reliability.
Data Analysis & Management: Organize and analyze large-scale datasets to identify trends, extract insights, and improve existing techniques using computational statistics.
Cross-Functional Collaboration: Partner with internal teams, the NIST standards consortium, and external stakeholders to share expertise and communicate technical findings.
Strategic Evaluation: Use professional judgment to assess and apply precedents, weighing the strengths and weaknesses of various computational methods.

Requirements

Conditions of employment

U.S. citizenship
Males born after 12-31-59 must be registered for Selective Service
Suitable for Federal employment
Bargaining Unit Position: No

Qualifications

Basic Requirements:

A. Bachelor's degree in computer science.

OR

B. Bachelor's degree with 30 semester hours in a combination of mathematics, statistics, and computer science. At least 15 of the 30 semester hours must have included any combination of statistics and mathematics that included differential and integral calculus. All academic degrees and course work must be from accredited or pre-accredited institutions.

AND

In addition to the basic requirements:

Applicants must have one year (52 weeks) of specialized experience equivalent to at least the GS-9 level (ZP-II at NIST). Specialized experience is defined as experience in developing and implementing artificial intelligence or machine learning solutions; programming in Python, R, or Java; and analyzing high-dimensional biological data, including flow cytometry and genomic datasets.

OR

3 years of progressively higher level graduate education leading to a Ph.D. degree or Ph.D. or equivalent doctoral degree.

OR

Combination of education and experience.

Experience refers to paid and unpaid experience, including volunteer work done through National Service programs (e.g., Peace Corps, AmeriCorps) and other organizations (e.g., professional; philanthropic; religious; spiritual; community, student, social). Volunteer work helps build critical competencies, knowledge, and skills and can provide valuable training and experience that translates directly to paid employment. You will receive credit for all qualifying experience, including volunteer experience.

The qualification requirements in this vacancy announcement are based on the U.S. Office of Personnel Management (OPM) Qualification Standards Handbook.

If requesting reconsideration of your qualification determination, please refer to the following site: Applicant Reconsideration

Education

This position has an education requirement. Transcripts must be submitted to validate that the education requirement has been met. Unofficial transcripts will be accepted in the application package. However, an official copy will be required before a final offer of employment.

Use of foreign education for qualifications. An accredited organization must evaluate education completed outside of the U.S. to ensure that it is comparable to education received in accredited institutions in the U.S. Click here to view a listing of accredited organizations from the Department of Education's website. A copy of the foreign education evaluation (containing the results with course-by-course listing) is required with your application.

Additional information

This position is covered under NIST's Alternative Personnel Management System (APMS), a pay-for-performance system with excellent HR flexibilities to help NIST recruit and retain top talent. Learn more about the APMS here!

We may share your application package with other selecting officials. Additional selections may be made through this vacancy.
Click all links in this vacancy announcement to view additional information or instructions.
You MUST select at least ONE ELIGIBILITY to be considered for this position.
All documents submitted for this announcement must be legible to make qualification or eligibility determinations.

A probationary period may be required.

NIST strives to build a flexible and encouraging work environment to bring out the best in our employees. To help our employees balance responsibilities at home and at work, NIST offers a variety of work-life flexibilities. For more information, please visit our Careers website.

Candidates should be committed to improving the efficiency of the Federal government, passionate about the ideals of our American republic, and committed to upholding the rule of law and the United States Constitution.

Benefits

A career with the U.S. government provides employees with a comprehensive benefits package. As a federal employee, you and your family will have access to a range of benefits that are designed to make your federal career very rewarding. Opens in a new windowLearn more about federal benefits.

Review our benefits

Eligibility for benefits depends on the type of position you hold and whether your position is full-time, part-time or intermittent. Contact the hiring agency for more information on the specific benefits offered.

How you will be evaluated

You will be evaluated for this job based on how well you meet the qualifications above.

Please prepare a resume that is no longer than two pages; only the first two pages will be considered during the review process. Ensure your font is 11 points or larger and upload your resume as a .pdf document. This helps ensure your formatting looks exactly the way you intended.

How you will be evaluated: You will be evaluated for this job based on how well you meet the qualifications above. Once the announcement has closed, a review of your resume and supporting documentation will be used to determine whether you meet the qualification requirements listed in this announcement. Overstating your qualifications and/or experience in your application materials or application questionnaire may result in your removal from consideration.

A Subject Matter Experts (SMEs) may be used to review your resume to determine your technical qualifications for this position based on the required specialized experience. SMEs will review ONLY two (2) pages of your resume. SMEs will not review additional information beyond your resume.

Applications will be assessed on the following competencies:

Attention to Detail
Technical Competence
Technology Application

Referral: All applicants may be referred to the selecting official for consideration. Under Direct Hire Authority, applicants are not rated and ranked, and veteran preference does not apply.

CTAP or ICTAP eligibility: If you are a displaced or surplus Federal employee eligible for the Career Transition Assistance Plan (CTAP) or Interagency Career Transition Assistance Plan (ICTAP), you must be determined eligible and rated as well-qualified to receive special selection priority. "Well Qualified" means that in addition to meeting the minimum qualification requirements and selective placement factor(s), if applicable, you must receive a score of 85 or higher. Please review the following site regarding required documents to support CTAP or ICTAP eligibility and additional information regarding this authority - Section 8: Hiring Paths at NIST | NIST

Required Documents

The documents required may vary based on how you're applying (i.e., as a veteran or disabled veteran, current or former Federal employee, etc.). Please review the Required Documents for this position to find out if there are any documents required with your application. Failure to submit required documents, based upon how you apply, may result in loss of consideration due to an incomplete application package.

A complete application includes: 1) A resume (not to exceed two pages), 2) vacancy question responses regarding technical qualifications, and 3) submission of any required documents. Please note that if you do not provide all required information, as specified in this announcement, or if the documents submitted are illegible you may not be considered for this position (or may not receive the special consideration for which you may be eligible).

Resume: All applicants must submit a resume by creating one in USAJOBS or uploading one of their choosing. Please prepare a resume no longer than 2 pages; only the first 2 pages will be considered during the review process. Ensure your font is 11 points or larger and upload your resume as a .pdf document. This helps ensure your formatting looks exactly the way you intended. Cover letters are optional. To receive any credit for relevant experience, please list the month/year and the number of hours worked for experience listed on your resume. We suggest you review the qualification requirements for this position as you may need to customize your resume to ensure that it supports the position qualifications. Please refer to the Resume Guidance on how to build an effective resume.

How to Apply

Please read the entire announcement and all the instructions before you begin an application. To apply and be considered for this position, you must complete all required questionnaires, assessments, and required documentation as specified in the How to Apply and Required Documents section. The complete application package must be submitted by 11:59 PM (ET) on the closing date of the announcement to receive consideration. The application process is as follows:

Click the Apply Online button.

Answer the questions presented in the application and attach all necessary supporting documentation.

Click the Submit Application button prior to 11:59 PM (ET) on the announcement closing date.

As part of the application process, you will be asked to respond to four narrative questions. While your responses to these questions is not required and will not be scored, we encourage you to thoughtfully address each question. You will be asked to certify that you are using your own words and did not use a consultant or artificial intelligence (AI) such as a large language model (LLM) like ChatGPT or Copilot.

Once your application has been submitted, you will receive a confirmation notification by email. The Human Resources Office will evaluate your application to determine your eligibility for the position. After the evaluation is complete, you will receive another notification regarding the status of your application.

To update your application, including supporting documentation: During the announcement open period, return to your USAJOBS account, find your application record, and click Edit my application. This option will no longer be available once the announcement has closed.

To view the announcement status or your application status: Click on this: USAJOBS Help Center - How to see your application and job status Your application status page is where you can view your application status, USA Hire assessment completion status, and review your notifications sent by the hiring agency regarding your application.

Need help applying?

If you are experiencing any difficulties with the online application process (anything after you have clicked the 'Apply Online' button), please contact the Agency Contact listed on this announcement between regular business hours (8:00 a.m. - 4:00 p.m. ET). If you receive any kind of error message, please be ready to provide a screenshot or, at a minimum, the error message text and number. We will provide you with a technical support number for further assistance if necessary.
If you are having trouble with USAJOBS (searching for jobs, account password/profile issues, or Resume Builder), please visit the USAJOBS USAJOBS Help Center - How to.... We regret that we are unable to support any issues with USAJOBS, as this service is not maintained by the NIST.
If you are experiencing a significant hardship that hinders your ability to apply online, please contact the Agency Contact listed on this announcement prior to the vacancy closing date and during regular business hours to discuss your situation.

Agency contact information

Jason Travis

jason.travis@nist.gov

Address

Biosystems and Biomaterials Division
100 Bureau Drive
Gaithersburg, MD 20899
US

Next steps

We will update applicant statuses when:

A qualification determination is made. If found not qualified/eligible, no additional updates will be provided.
Applications are referred to the selecting official.
A selection decision has been made.

Please notify us if your contact information changes after announcement's closing date. Also, note that if you provide an inaccurate email address or if your mailbox is full or blocked (e.g., spam-blocker), you may not receive important communication, which could affect your consideration for this position.

Overview

Accepting applications

Open & closing dates

05/12/2026 to 05/18/2026

Salary

$85,447 - $133,142 per year

Pay scale & grade

ZP 3

Location

1 vacancy in the following location:

Gaithersburg, MD

Remote job

Telework eligible

Yes—as determined by the agency policy.

Travel Required

Not required

Relocation expenses reimbursed

Appointment type

Permanent

Work schedule

Full-time

Service

Competitive

Promotion potential

Job family (Series)

1550 Computer Science

Supervisory status

Security clearance

Not Required

Drug test

Position sensitivity and risk

Non-sensitive (NS)/Low Risk

Trust determination process

Suitability/Fitness

Financial disclosure

Bargaining unit status

Announcement number

MML-644-26-12954428-DH

Control number

868757900

US National Institute of Standards and Technology jobs

Bioinformatician / AI x BIO

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